Premium Aesthetic Clinic
Polynucleotide Treatment in Liverpool
Polynucleotides repair skin quality from within, improving hydration, firmness and the fine crepiness that filler cannot address. Delivered as a planned course at our medically-led Liverpool clinic.
Medically Led
Natural Results
Certified Experts
Qualified Practitioners
Liverpool Clinic
In-Depth Consultations
Aftercare Support
Fully Insured
What Are Polynucleotides?
Polynucleotides are purified DNA fragments, most often derived from salmon or trout, whose structure is close enough to human DNA to be recognised and used by your own cells. They are injected into the skin rather than beneath it, where they act as a signal to repair.
Rather than adding volume, they prompt fibroblasts to produce collagen and elastin and improve the skin's ability to hold water. That makes them a regenerative treatment: the improvement comes from your own tissue responding, not from the product occupying space.
This is why polynucleotides suit thin, crepey or damaged skin where filler would look wrong, particularly around the eyes. Results build across a course of three sessions and continue developing for weeks after the last one.

Treatment Time
30 to 45 Minutes

Downtime
24 to 48 Hours

Longevity
6 to 9 Months

Prices From
£238.80
Benefits of Polynucleotides
A regenerative treatment for skin quality, suited to areas too delicate for conventional filler.
Improves thin, crepey skin
Thickens and strengthens skin that has become fragile, particularly under the eyes and on the neck.
Stimulates collagen and elastin
Prompts your own fibroblasts to rebuild, so firmness improves gradually and holds after the course finishes.
Deep, lasting hydration
Improves how well the skin retains water, which softens fine lines caused by dehydration rather than movement.
Calms reactive skin
Useful alongside rosacea and post-inflammatory pigmentation, where stronger resurfacing would risk a flare.
Areas We Can Treat
Polynucleotides are priced by area. Most patients begin with the area that concerns them most and extend the plan once they see how their skin responds.
Under-Eye Area
The most requested area, improving crepiness, dark shadowing and thin skin where filler often looks puffy.
Full Face
Overall improvement in firmness, hydration and texture across the whole face.
Neck
Softens the horizontal lines and loose texture that age the neck ahead of the face.
Decolletage
Treats sun damage and the fine vertical creping that develops on the chest.
Hands
Improves skin thickness and quality on the back of the hands.
Scalp
Used to improve the condition of the scalp alongside treatment for thinning hair.
Who Is This Treatment Suitable For?
Suitability and the right number of sessions are confirmed by your practitioner at a full medical consultation.
Generally Suitable For
Thin, crepey or dehydrated skin
Under-eye hollowing where filler is not appropriate
Early loss of firmness and elasticity
Skin recovering from sun damage or inflammation
Not Suitable For
Known allergy to fish or fish-derived products
Active infection or inflammation at the site
Autoimmune conditions without medical clearance
Pregnancy or breastfeeding
Meet Your Expert
Catlin
Founder & Lead Aesthetic Practitioner
Degree in Aesthetic Medicine • Level 7 Aesthetic Practitioner
Before and After Results Polynucleotides Liverpool
Polynucleotide Prices in Liverpool
Priced per treatment area. Polynucleotides work as a course, so your practitioner will plan the full schedule at your first appointment.
Typical course: 3 sessions, 2 to 3 weeks apart
Polynucleotides are a regenerative course rather than a one-off. A top-up every 6 to 9 months holds the result. Pricing for a course booked in advance is confirmed at your consultation.
Real results from our clinic. Individual results may vary.
Before
After 2 Weeks
Treatment: Polynucleotides to the under-eye area
Patient Experiences
Hear from our clients about their treatments in our Liverpool clinic.
Read all Google Reviews
“I have had 2 treatments with Jennifer so far & both sessions have been informative & relaxing. She creates a nice atmosphere & puts you at ease. Jennifer is a credit to your team & look forward to seeing her again
Thank you.”
L
Housewife
“I have had a few treatments now with Catlin and I have to say she is absolutely amazing!! She made me feel very welcome and took the time to explain in detail how each treatment worked. She is very professional, but down to earth at the same!
The clinic is beautiful, extremely well equipped and leaves you feeling like you’ve been well and truly pampered. I 100% recommend Derma Cosmedic.”
F
Manager
“The 2 staff were friendly and informative and made me feel at ease during the procedure will be returning again.”
S
Steve Hill.
Electrician
What to Expect
1
Skin and Medical Consultation
Your practitioner assesses skin thickness and quality, checks for fish allergy and explains how many sessions your concern is likely to need.
2
Planning the Course
Polynucleotides work cumulatively, so the full schedule is agreed upfront, usually three sessions two to three weeks apart.
3
The Treatment
Small amounts are placed into the skin with a fine needle or cannula. Numbing cream is applied first, and most clients describe brief stinging as each point is placed.
4
Recovery and Review
Small bumps settle within a day and any bruising within a week. Your practitioner reviews progress at each session and again after the course.
Safety, Side Effects and Aftercare
Clinical Safety
Polynucleotides are injected, so they are treated as a medical procedure here. Products are sourced from regulated suppliers, prepared under sterile conditions and administered only by qualified injectors.
Because the product is derived from fish DNA, allergy screening is part of every consultation. If there is any doubt about your history we will not proceed on the day.

Potential Side Effects
Reactions are usually confined to the injection points and settle within a few days:
Small raised bumps for up to 24 hours
Bruising at the injection points
Mild swelling or tenderness

Essential Aftercare
Avoid makeup over the area for 12 hours
Skip the gym, sauna and alcohol for 24 hours
Sleep on your back on the first night if treated under the eyes
Complete the full course to get the result you were quoted
Why Choose Derma Cosmedic?
Expert Practitioners
Treatments administered only by highly qualified medical professionals.
Bespoke Plans
No cookie-cutter approaches. We treat your specific anatomy and goals.
Natural Outcomes
Our signature is a refreshed look. We enhance, rather than change, your appearance.
Premium Products
We only use genuine, industry-leading brands sourced from licensed pharmacies.
Unrivalled Aftercare
We provide comprehensive support and complimentary review appointments.
Trusted in Liverpool
A leading reputation built on hundreds of 5-star reviews from local clients.
Polynucleotide Clinic in Liverpool
Situated centrally, Derma Cosmedic is easily accessible for clients across Liverpool, Merseyside, and the North West. Our discreet, state-of-the-art clinic provides a safe and welcoming environment for all your aesthetic needs.

Derma Cosmedic Clinic
6-8 Castle St, Liverpool L2 0NB

Ample nearby parking and a 5-minute walk from the central stations.
Complementary Treatments
Frequently Asked Questions
What are polynucleotide treatments, and how do they work?+
What skin concerns can polynucleotides help with?+
What’s the difference between polynucleotides and fillers like hyaluronic acid?+
Is the treatment suitable for all skin types and ages?+
When will I start seeing results, and how long do they last?+
Are polynucleotide treatments safe?+
How much does polynucleotides cost in Liverpool?+
Do you offer payment plans?+
Meet the Derma Cosmedic Team
A medically-led team of aesthetic practitioners, laser technicians and clinic experts, based at 6-8 Castle Street, Liverpool. Each member brings clinical training, industry experience and a commitment to natural, results-driven care.
Honest advice. Ethical aesthetics. Exceptional results.
At Derma Cosmedic, we believe trust is everything. You’ll never be pressured into treatments you don’t need or procedures that won’t benefit you — our recommendations are always based on clinical expertise, evidence and what is genuinely best for your skin, your health and your long-term results.
Based on Castle Street in Liverpool city centre, our medically-led team delivers every treatment to the highest clinical standard, with a focus on natural, confidence-building results.
More about Derma Cosmedic

